Rethinking Federated Prompt Learning for Medical Images: From Textual Tuning to Visual Manifold Anchoring
Yipan Wei, Wenke Huang, Yapeng Li, He Li, Qixin Zhang, Mang Ye, Bo Du
ICML 2026 regular
Abstract (source: OpenReview · © authors)
Federated Prompt Learning (FPL) adapts Vision-Language Models to privacy-sensitive medical imaging, typically via a textual tuning paradigm that assumes the frozen visual encoder provides a discriminative feature geometry. We argue this assumption breaks down in medical settings, leading to two geometric pathologies: (1) Intra-client: Medical Manifold Collapse, where high morphological similarity reduces the effective rank of visual features; and (2) Inter-client: Medical Topological Misalignment, where heterogeneous acquisition protocols induce inconsistent geometry across clients. To address these, we propose FedMAP, which shifts the paradigm to Visual Manifold Anchoring. FedMAP utilizes an LLM-derived codebook as a client-invariant synchronization signal to restructure the visual space, via Manifold Semantic Anchoring (MSA) and Topology Structural Alignment (TSA) to enforce consistent inter-class relations. Experiments on FedISIC, FedCamelyon17, and a private ultrasound dataset show that FedMAP consistently outperforms state-of-the-art methods, especially in high-noise regimes where manifold collapse is most severe.
Keywords
Metadata from BioTender-max/icml2026-ai-bio (CC0-1.0). Phở does not host any PDF; links point back to the source.
Related
Beyond Continuity: Simulation-free Reconstruction of Discrete Branching Dynamics from Single-cell Snapshots
Junda Ying, Yuxuan Wang, Bowen Yang, Peijie Zhou +1
Inferring cellular trajectories from destructive snapshots is complicated by the challenges of stochasticity and non-conservative mass dynamics such as cell proliferation and…
Deep Learning for BioImaging: What Are We Really Learning?
Ivan Svatko, Maxime Sanchez, Ihab Bendidi, Gilles Cottrell +1
Representation learning has driven major advances in natural image analysis by enabling models to acquire high-level semantic features. In microscopy imaging, however, it remains…
Are We Overconfident in Models and Results for Semi-Supervised 3D Medical Image Segmentation?
Jun Li, Ziwei Qin
Semi-supervised learning has become a dominant paradigm for reducing annotation costs. However, we argue that the current progress is clouded by a twofold overconfidence problem.…