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Discontinuous Galerkin Neural Operator for Pathology Defocus Deblurring

Shaoqing Duan, Haofei Song, Xintian Mao, Qingli Li, Yan Wang

ICML 2026 regular

Tóm tắt (nguồn: OpenReview · © tác giả)

Defocus deblurring in pathological microscopy remains challenging due to the spatially varying and locally discontinuous nature of optical blur induced by a position-dependent integral imaging process. Existing deep learning methods, constrained by shift-invariance assumptions and limited interpretability, are not well suited to such heterogeneous blur patterns. Neural operators provide a principled alternative by modeling defocus formation directly as an integral operator, offering a new perspective on defocus deblurring. However, most existing neural operator architectures for low-level vision rely on globally parameterized kernels that assume smoothness and stationarity, limiting their ability to model heterogeneous and locally discontinuous blur patterns. To address this limitation, we propose the Discontinuous Galerkin Neural Operator (DGNO), which parameterizes the integral kernel using a discontinuous Galerkin formulation with element-local volume operators and interface numerical fluxes. DGNO provides a principled combination of locality, heterogeneity modeling, and global coherence while preserving the underlying physics of optical image formation. Extensive experiments demonstrate that DGNO surpasses state-of-the-art methods, delivering sharper reconstructions, robust handling of spatially varying blur, and scalable high-resolution performance.

Từ khoá

Defocus Deblurring Pathology

Metadata từ BioTender-max/icml2026-ai-bio (CC0-1.0). Phở không lưu trữ bản PDF; link trỏ về nguồn gốc.

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